Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype

Patients with hypophosphatemia rickets (including DMP1 mutations) develop severe osteoarthritis (OA), although the mechanism is largely unknown. In this study, we first identified the expression of DMP1 in hypertrophic chondrocytes using immunohistochemistry (IHC) and X-gal analysis of Dmp1-knockout...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Lin, Shuxian, Liu, Ying, Yuan, Baozhi, Harris, Steph E, Feng, Jian Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442/
https://www.ncbi.nlm.nih.gov/pubmed/27766035
http://dx.doi.org/10.7150/ijbs.15833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442/
https://www.ncbi.nlm.nih.gov/pubmed/27766035
http://dx.doi.org/10.7150/ijbs.15833

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