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Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype
Patients with hypophosphatemia rickets (including DMP1 mutations) develop severe osteoarthritis (OA), although the mechanism is largely unknown. In this study, we first identified the expression of DMP1 in hypertrophic chondrocytes using immunohistochemistry (IHC) and X-gal analysis of Dmp1-knockout...
Autores principales: | Zhang, Qi, Lin, Shuxian, Liu, Ying, Yuan, Baozhi, Harris, Steph E, Feng, Jian Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442/ https://www.ncbi.nlm.nih.gov/pubmed/27766035 http://dx.doi.org/10.7150/ijbs.15833 |
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