Indoxyl Sulfate Enhance the Hypermethylation of Klotho and Promote the Process of Vascular Calcification in Chronic Kidney Disease

Chronic kidney disease (CKD) is a state of Klotho deficiency. The Klotho expression may be suppressed due to DNA hypermethylation in cancer cells so we have investigated the effects and possible mechanisms by which Klotho expression is regulated in human aortic smooth muscle cells (HASMCs). The vasc...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Zhang, Xiaoyan, Zhang, Han, Liu, Tongqiang, Zhang, Hui, Teng, Jie, Ji, Jun, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069445/
https://www.ncbi.nlm.nih.gov/pubmed/27766038
http://dx.doi.org/10.7150/ijbs.15195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069445/
https://www.ncbi.nlm.nih.gov/pubmed/27766038
http://dx.doi.org/10.7150/ijbs.15195

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