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A rare schizophrenia risk variant of CACNA1I disrupts Ca(V)3.3 channel activity
CACNA1I is a candidate schizophrenia risk gene. It encodes the pore-forming human Ca(V)3.3 α1 subunit, a subtype of voltage-gated calcium channel that contributes to T-type currents. Recently, two de novo missense variations, T797M and R1346H, of hCa(V)3.3 were identified in individuals with schizop...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069464/ https://www.ncbi.nlm.nih.gov/pubmed/27756899 http://dx.doi.org/10.1038/srep34233 |