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A rare schizophrenia risk variant of CACNA1I disrupts Ca(V)3.3 channel activity

CACNA1I is a candidate schizophrenia risk gene. It encodes the pore-forming human Ca(V)3.3 α1 subunit, a subtype of voltage-gated calcium channel that contributes to T-type currents. Recently, two de novo missense variations, T797M and R1346H, of hCa(V)3.3 were identified in individuals with schizop...

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Detalles Bibliográficos
Autores principales:	Andrade, A., Hope, J., Allen, A., Yorgan, V., Lipscombe, D., Pan, J. Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069464/ https://www.ncbi.nlm.nih.gov/pubmed/27756899 http://dx.doi.org/10.1038/srep34233

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