Chronic stress prior to pregnancy potentiated long-lasting postpartum depressive-like behavior, regulated by Akt-mTOR signaling in the hippocampus

Postpartum depression (PPD) affects over 10% of new mothers and adversely impacts the health of offspring. One of the greatest risk factors for PPD is prepregnancy stress but the underlying biological mechanism is unknown. Here we constructed an animal model which recapitulated prepregnancy stress i...

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Detalles Bibliográficos
Autores principales: Xia, Baomei, Chen, Chang, Zhang, Hailou, Xue, Wenda, Tang, Juanjuan, Tao, Weiwei, Wu, Ruyan, Ren, Li, Wang, Wei, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069466/
https://www.ncbi.nlm.nih.gov/pubmed/27756905
http://dx.doi.org/10.1038/srep35042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069466/
https://www.ncbi.nlm.nih.gov/pubmed/27756905
http://dx.doi.org/10.1038/srep35042

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