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A rare subset of skin-tropic regulatory T cells expressing Il10/Gzmb inhibits the cutaneous immune response

Foxp3(+) regulatory T cells (Tregs) migrating from the skin to the draining lymph node (dLN) have a strong immunosuppressive effect on the cutaneous immune response. However, the subpopulations responsible for their inhibitory function remain unclear. We investigated single-cell gene expression hete...

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Detalles Bibliográficos
Autores principales: Ikebuchi, Ryoyo, Teraguchi, Shunsuke, Vandenbon, Alexis, Honda, Tetsuya, Shand, Francis H. W., Nakanishi, Yasutaka, Watanabe, Takeshi, Tomura, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069467/
https://www.ncbi.nlm.nih.gov/pubmed/27756896
http://dx.doi.org/10.1038/srep35002