Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes

Cell and animal studies have demonstrated that circadian rhythm is governed by autonomous rhythmicity of clock genes. Although disturbances in circadian rhythm have been implicated in metabolic disease development, it remains unknown whether muscle circadian rhythm is altered in human models of type...

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Detalles Bibliográficos
Autores principales: Hansen, Jan, Timmers, Silvie, Moonen-Kornips, Esther, Duez, Helene, Staels, Bart, Hesselink, Matthijs K. C., Schrauwen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069469/
https://www.ncbi.nlm.nih.gov/pubmed/27756900
http://dx.doi.org/10.1038/srep35047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069469/
https://www.ncbi.nlm.nih.gov/pubmed/27756900
http://dx.doi.org/10.1038/srep35047

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