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LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)

Nonalcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease, manifests as an over-accumulation of hepatic fat. We have recently shown that mice with genetic knockout of a long non-coding RNA (lncRNA) steroid receptor RNA activator (SRA) (SRAKO) are resistant to high fat d...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Yu, Dongsheng, Nian, Xue, Liu, Junyi, Koenig, Ronald J., Xu, Bin, Sheng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069493/
https://www.ncbi.nlm.nih.gov/pubmed/27759039
http://dx.doi.org/10.1038/srep35531