CDK4 regulates cancer stemness and is a novel therapeutic target for triple-negative breast cancer

Triple negative breast cancers exhibit very aggressive features and poor patient outcomes. These tumors are enriched in cancer stem cells and exhibit resistance to most treatments and chemotherapy. In this study, we found the cyclin-dependent kinase (CDK4) to act as a cancer stem cell regulator and...

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Detalles Bibliográficos
Autores principales: Dai, Meiou, Zhang, Chenjing, Ali, Ayad, Hong, Xinyuan, Tian, Jun, Lo, Chieh, Fils-Aimé, Nadège, Burgos, Sergio A., Ali, Suhad, Lebrun, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069501/
https://www.ncbi.nlm.nih.gov/pubmed/27759034
http://dx.doi.org/10.1038/srep35383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069501/
https://www.ncbi.nlm.nih.gov/pubmed/27759034
http://dx.doi.org/10.1038/srep35383

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