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The effects of proteasomal inhibition on synaptic proteostasis

Synaptic function crucially depends on uninterrupted synthesis and degradation of synaptic proteins. While much has been learned on synaptic protein synthesis, little is known on the routes by which synaptic proteins are degraded. Here we systematically studied how inhibition of the ubiquitin‐protea...

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Detalles Bibliográficos
Autores principales: Hakim, Vicky, Cohen, Laurie D, Zuchman, Rina, Ziv, Tamar, Ziv, Noam E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069550/
https://www.ncbi.nlm.nih.gov/pubmed/27613546
http://dx.doi.org/10.15252/embj.201593594