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Synthesis of Arylazide‐ and Diazirine‐Containing CrAsH‐EDT(2) Photoaffinity Probes

Two photo‐crosslinking biarsenical (CrAsH‐EDT(2))‐modified probes were synthesized that are expected to be useful tools for tetracysteine‐labeled proteins to facilitate the co‐affinity purification of their DNA binding sequences and interacting proteins. In addition, improvements for the synthesis o...

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Detalles Bibliográficos
Autores principales: Syeda, Shameem S., Rice, Daren, Hook, Derek J., Heckert, Leslie L., Georg, Gunda I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069617/
https://www.ncbi.nlm.nih.gov/pubmed/26948688
http://dx.doi.org/10.1002/ardp.201500440