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A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

Circulating tumor cells (CTCs) were introduced as biomarkers more than 10 years ago, but capture of viable CTCs at high purity from peripheral blood of cancer patients is still a major technical challenge. Here, we report a novel microfluidic platform designed for marker independent capture of CTCs....

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Detalles Bibliográficos
Autores principales: Hvichia, G.E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R.P.L., Stoecklein, N.H., Wikman, H., Riethdorf, S., Pantel, K., Gorges, T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069649/
https://www.ncbi.nlm.nih.gov/pubmed/26789903
http://dx.doi.org/10.1002/ijc.30007