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Transient Induced Molecular Electronic Spectroscopy (TIMES) for study of protein-ligand interactions

We present a method, Transient Induced Molecular Electronic Spectroscopy (TIMES), to detect protein-ligand interactions without any protein engineering or chemical modification. We developed a physics model for the TIMES signal and mathematically formulated the problem to attain physical insight of...

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Detalles Bibliográficos
Autores principales: Zhang, Tiantian, Ku, Ti-Hsuan, Han, Yuanyuan, Subramanian, Ramkumar, Niaz, Iftikhar Ahmad, Luo, Hua, Chang, Derrick, Huang, Jian-Jang, Lo, Yu-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069662/
https://www.ncbi.nlm.nih.gov/pubmed/27759045
http://dx.doi.org/10.1038/srep35570