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Transient Induced Molecular Electronic Spectroscopy (TIMES) for study of protein-ligand interactions
We present a method, Transient Induced Molecular Electronic Spectroscopy (TIMES), to detect protein-ligand interactions without any protein engineering or chemical modification. We developed a physics model for the TIMES signal and mathematically formulated the problem to attain physical insight of...
Autores principales: | Zhang, Tiantian, Ku, Ti-Hsuan, Han, Yuanyuan, Subramanian, Ramkumar, Niaz, Iftikhar Ahmad, Luo, Hua, Chang, Derrick, Huang, Jian-Jang, Lo, Yu-Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069662/ https://www.ncbi.nlm.nih.gov/pubmed/27759045 http://dx.doi.org/10.1038/srep35570 |
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