Zinc(II) Binding Site to the Amyloid-β Peptide: Insights from Spectroscopic Studies with a Wide Series of Modified Peptides

[Image: see text] The Zn(II) ion has been linked to Alzheimer’s disease (AD) due to its ability to modulate the aggregating properties of the amyloid-β (Aβ) peptide, where Aβ aggregation is a central event in the etiology of the disease. Delineating Zn(II) binding properties to Aβ is thus a prerequi...

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Detalles Bibliográficos
Autores principales: Alies, Bruno, Conte-Daban, Amandine, Sayen, Stéphanie, Collin, Fabrice, Kieffer, Isabelle, Guillon, Emmanuel, Faller, Peter, Hureau, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069684/
https://www.ncbi.nlm.nih.gov/pubmed/27665863
http://dx.doi.org/10.1021/acs.inorgchem.6b01733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069684/
https://www.ncbi.nlm.nih.gov/pubmed/27665863
http://dx.doi.org/10.1021/acs.inorgchem.6b01733

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