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Single and Transient Ca(2+) Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion

Chronic alterations in calcium (Ca(2+)) signalling in podocytes have been shown to cause proteinuria and progressive glomerular diseases. However, it is unclear whether short Ca(2+) peaks influence glomerular biology and cause podocyte injury. Here we generated a DREADD (Designer Receptor Exclusivel...

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Detalles Bibliográficos
Autores principales: Koehler, Sybille, Brähler, Sebastian, Kuczkowski, Alexander, Binz, Julia, Hackl, Matthias J., Hagmann, Henning, Höhne, Martin, Vogt, Merly C., Wunderlich, Claudia M., Wunderlich, F. Thomas, Schweda, Frank, Schermer, Bernhard, Benzing, Thomas, Brinkkoetter, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069688/
https://www.ncbi.nlm.nih.gov/pubmed/27759104
http://dx.doi.org/10.1038/srep35400