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A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma

Purpose: To evaluate the safety and ocular hypotensive efficacy of 4 trabodenoson doses administered twice daily over 14 or 28 days in subjects with ocular hypertension or primary open-angle glaucoma (POAG). Methods: In this multicenter, randomized, double-masked, placebo-controlled, dose-escalation...

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Detalles Bibliográficos
Autores principales: Myers, Jonathan S., Sall, Kenneth N., DuBiner, Harvey, Slomowitz, Natanya, McVicar, William, Rich, Cadmus C., Baumgartner, Rudolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069706/
https://www.ncbi.nlm.nih.gov/pubmed/27002298
http://dx.doi.org/10.1089/jop.2015.0148