A Randomized Phase 1 Dose Escalation Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Trabodenoson in Healthy Adult Volunteers

Purpose: To investigate the safety, tolerability, and pharmacokinetics of trabodenoson, a highly selective adenosine mimetic targeting the adenosine A(1) receptor. Methods: In Part 1, 60 healthy adult volunteers were randomized to 14 days of twice-daily topical monocular application of placebo or tr...

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Detalles Bibliográficos
Autores principales: Laties, Alan, Rich, Cadmus C., Stoltz, Randall, Humbert, Vernon, Brickman, Chaim, McVicar, William, Baumgartner, Rudolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069726/
https://www.ncbi.nlm.nih.gov/pubmed/27046445
http://dx.doi.org/10.1089/jop.2015.0147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069726/
https://www.ncbi.nlm.nih.gov/pubmed/27046445
http://dx.doi.org/10.1089/jop.2015.0147

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