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An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria

Microorganisms are a rich source of bioactives; however, chemical identification is a major bottleneck. Strategies that can prioritize the most prolific microbial strains and novel compounds are of great interest. Here, we present an integrated approach to evaluate the biosynthetic richness in bacte...

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Detalles Bibliográficos
Autores principales: Maansson, Maria, Vynne, Nikolaj G., Klitgaard, Andreas, Nybo, Jane L., Melchiorsen, Jette, Nguyen, Don D., Sanchez, Laura M., Ziemert, Nadine, Dorrestein, Pieter C., Andersen, Mikael R., Gram, Lone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069768/
https://www.ncbi.nlm.nih.gov/pubmed/27822535
http://dx.doi.org/10.1128/mSystems.00028-15