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A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease

Greater understanding of the functions of host gene products in response to infection is required. While many of these genes enable pathogen clearance, some enhance pathogen growth or contribute to disease symptoms. Many studies have profiled transcriptomic and proteomic responses to infection, gene...

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Detalles Bibliográficos
Autores principales: McDonald, Jacqueline U., Kaforou, Myrsini, Clare, Simon, Hale, Christine, Ivanova, Maria, Huntley, Derek, Dorner, Marcus, Wright, Victoria J., Levin, Michael, Martinon-Torres, Federico, Herberg, Jethro A., Tregoning, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069771/
https://www.ncbi.nlm.nih.gov/pubmed/27822537
http://dx.doi.org/10.1128/mSystems.00051-16