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A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease
Greater understanding of the functions of host gene products in response to infection is required. While many of these genes enable pathogen clearance, some enhance pathogen growth or contribute to disease symptoms. Many studies have profiled transcriptomic and proteomic responses to infection, gene...
Autores principales: | McDonald, Jacqueline U., Kaforou, Myrsini, Clare, Simon, Hale, Christine, Ivanova, Maria, Huntley, Derek, Dorner, Marcus, Wright, Victoria J., Levin, Michael, Martinon-Torres, Federico, Herberg, Jethro A., Tregoning, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069771/ https://www.ncbi.nlm.nih.gov/pubmed/27822537 http://dx.doi.org/10.1128/mSystems.00051-16 |
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