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Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses

BACKGROUND: Vaccination generating a robust memory population of CD8(+) T cells may provide protection against cancer. However, immune therapies for cancer are influenced by the local tumour immune microenvironment. An infiltrate of T cells into tumours of people with colorectal cancer has proven to...

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Detalles Bibliográficos
Autores principales: Highton, Andrew J., Girardin, Adam, Bell, Georgia M., Hook, Sarah M., Kemp, Roslyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069793/
https://www.ncbi.nlm.nih.gov/pubmed/27756214
http://dx.doi.org/10.1186/s12865-016-0178-4