Size polymorphism and low sequence diversity in the locus encoding the Plasmodium vivax rhoptry neck protein 4 (PvRON4) in Colombian isolates

BACKGROUND: Designing a vaccine against Plasmodium vivax has focused on selecting antigens involved in invasion mechanisms that must have domains with low polymorphism for avoiding allele-specific immune responses. The rhoptry neck protein 4 (RON4) forms part of the tight junction, which is essentia...

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Detalles Bibliográficos
Autores principales: Buitrago, Sindy P., Garzón-Ospina, Diego, Patarroyo, Manuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069803/
https://www.ncbi.nlm.nih.gov/pubmed/27756311
http://dx.doi.org/10.1186/s12936-016-1563-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069803/
https://www.ncbi.nlm.nih.gov/pubmed/27756311
http://dx.doi.org/10.1186/s12936-016-1563-4

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