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Hepatocellular carcinoma-targeted drug discovery through image-based phenotypic screening in co-cultures of HCC cells with hepatocytes

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant cancers worldwide and is associated with substantial mortality. Because HCCs have strong resistance to conventional chemotherapeutic agents, novel therapeutic strategies are needed to improve survival in HCC patients. MET...

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Detalles Bibliográficos
Autores principales: Jang, Jae-Woo, Song, Yeonhwa, Kim, Kang Mo, Kim, Jin-Sun, Choi, Eun Kyung, Kim, Joon, Seo, Haengran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069815/
https://www.ncbi.nlm.nih.gov/pubmed/27756242
http://dx.doi.org/10.1186/s12885-016-2816-x