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Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse

BACKGROUND: A recently reported cocaine hydrolase (CocH3) fused with fragment crystallizable (Fc) region of human immunoglobulin G1, denoted as CocH3-Fc, is known as a promising therapeutic candidate for the treatment of cocaine overdose and addiction. A challenge for practical therapeutic use of th...

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Detalles Bibliográficos
Autores principales: Wang, Guojun, Zhang, Ting, Huang, Haifeng, Hou, Shurong, Chen, Xiabin, Zheng, Fang, Zhan, Chang-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069871/
https://www.ncbi.nlm.nih.gov/pubmed/27756365
http://dx.doi.org/10.1186/s12896-016-0302-9