Effects of early-life exposure to THIP on phenotype development in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a neurodevelopmental disorder caused mostly by disruptions in the MECP2 gene. MECP2-null mice show imbalances in neuronal excitability and synaptic communications. Several previous studies indicate that augmenting synaptic GABA receptors (GABA(A)Rs) can alleviate R...

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Detalles Bibliográficos
Autores principales: Zhong, Weiwei, Johnson, Christopher Mychal, Wu, Yang, Cui, Ningren, Xing, Hao, Zhang, Shuang, Jiang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069883/
https://www.ncbi.nlm.nih.gov/pubmed/27777634
http://dx.doi.org/10.1186/s11689-016-9169-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069883/
https://www.ncbi.nlm.nih.gov/pubmed/27777634
http://dx.doi.org/10.1186/s11689-016-9169-2

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