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RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
BACKGROUND: Aberrant expression of Retinoic acid receptor γ (RARγ) is implicated in cancer development. Our previous study identified that RARγ functions as a tumor promoter to drive hepatocellular carcinoma (HCC) growth. However, its contribution to HCC invasion and metastasis remains unclear. METH...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069892/ https://www.ncbi.nlm.nih.gov/pubmed/27756432 http://dx.doi.org/10.1186/s13046-016-0441-9 |