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Analysis of MDR genes expression and cross-resistance in eight drug resistant ovarian cancer cell lines

BACKGROUND: Multiple drug resistance (MDR) of cancer cells is the main reason of intrinsic or acquired insensitivity to chemotherapy in many cancers. In this study we used ovarian cancer model of acquired drug resistance to study development of MDR. We have developed eight drug resistant cell lines...

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Detalles Bibliográficos
Autores principales: Januchowski, Radosław, Sterzyńska, Karolina, Zaorska, Katarzyna, Sosińska, Patrycja, Klejewski, Andrzej, Brązert, Maciej, Nowicki, Michał, Zabel, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069986/
https://www.ncbi.nlm.nih.gov/pubmed/27756418
http://dx.doi.org/10.1186/s13048-016-0278-z