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Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS

BACKGROUND: Tumor cells are highly dependent on glucose even in the presence of oxygen. This concept called the Warburg effect is a hallmark of cancer and strategies are considered to therapeutically exploit the phenomenon such as ketogenic diets. The success of such strategies is dependent on a pro...

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Detalles Bibliográficos
Autores principales: Oppermann, Henry, Ding, Yonghong, Sharma, Jeevan, Berndt Paetz, Mandy, Meixensberger, Jürgen, Gaunitz, Frank, Birkemeyer, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070012/
https://www.ncbi.nlm.nih.gov/pubmed/27777605
http://dx.doi.org/10.1186/s12986-016-0131-9