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Metabolic response of glioblastoma cells associated with glucose withdrawal and pyruvate substitution as revealed by GC-MS
BACKGROUND: Tumor cells are highly dependent on glucose even in the presence of oxygen. This concept called the Warburg effect is a hallmark of cancer and strategies are considered to therapeutically exploit the phenomenon such as ketogenic diets. The success of such strategies is dependent on a pro...
Autores principales: | Oppermann, Henry, Ding, Yonghong, Sharma, Jeevan, Berndt Paetz, Mandy, Meixensberger, Jürgen, Gaunitz, Frank, Birkemeyer, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070012/ https://www.ncbi.nlm.nih.gov/pubmed/27777605 http://dx.doi.org/10.1186/s12986-016-0131-9 |
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