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Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia

Cognitive processing is highly dependent on the functional integrity of gamma-amino-butyric acid (GABA) interneurons in the brain. These cells regulate excitability and synaptic plasticity of principal neurons balancing the excitatory/inhibitory tone of cortical networks. Reduced function of parvalb...

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Detalles Bibliográficos
Autores principales: Alshammari, T K, Alshammari, M A, Nenov, M N, Hoxha, E, Cambiaghi, M, Marcinno, A, James, T F, Singh, P, Labate, D, Li, J, Meltzer, H Y, Sacchetti, B, Tempia, F, Laezza, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070049/
https://www.ncbi.nlm.nih.gov/pubmed/27163207
http://dx.doi.org/10.1038/tp.2016.66