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Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia
Cognitive processing is highly dependent on the functional integrity of gamma-amino-butyric acid (GABA) interneurons in the brain. These cells regulate excitability and synaptic plasticity of principal neurons balancing the excitatory/inhibitory tone of cortical networks. Reduced function of parvalb...
Autores principales: | Alshammari, T K, Alshammari, M A, Nenov, M N, Hoxha, E, Cambiaghi, M, Marcinno, A, James, T F, Singh, P, Labate, D, Li, J, Meltzer, H Y, Sacchetti, B, Tempia, F, Laezza, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070049/ https://www.ncbi.nlm.nih.gov/pubmed/27163207 http://dx.doi.org/10.1038/tp.2016.66 |
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