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Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development

BACKGROUND: Increased apposition of the frontal and parietal bones of the skull during embryogenesis may be a risk factor for the subsequent development of premature skull fusion, or craniosynostosis. Human craniosynostosis is a prevalent, and often serious embryological and neonatal pathology. Othe...

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Detalles Bibliográficos
Autores principales: Goldie, Stephen J., Arhatari, Benedicta D., Anderson, Peter, Auden, Alana, Partridge, Darren D., Jane, Stephen M., Dworkin, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070091/
https://www.ncbi.nlm.nih.gov/pubmed/27756203
http://dx.doi.org/10.1186/s12861-016-0136-7