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Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

BACKGROUND: The value of KI67 in breast cancer prognostication has been questioned due to concerns on the analytical validity of visual KI67 assessment and methodological limitations of published studies. Here, we investigate the prognostic value of automated KI67 scoring in a large, multicentre stu...

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Detalles Bibliográficos
Autores principales: Abubakar, Mustapha, Orr, Nick, Daley, Frances, Coulson, Penny, Ali, H. Raza, Blows, Fiona, Benitez, Javier, Milne, Roger, Brenner, Herman, Stegmaier, Christa, Mannermaa, Arto, Chang-Claude, Jenny, Rudolph, Anja, Sinn, Peter, Couch, Fergus J., Devilee, Peter, Tollenaar, Rob A. E. M., Seynaeve, Caroline, Figueroa, Jonine, Sherman, Mark E., Lissowska, Jolanta, Hewitt, Stephen, Eccles, Diana, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., Investigators, kConFab, Bolla, Manjeet K., Wang, Qin, Jones, Michael, Schoemaker, Minouk, Wesseling, Jelle, van Leeuwen, Flora E., Van ‘t Veer, Laura, Easton, Douglas, Swerdlow, Anthony J., Dowsett, Mitch, Pharoah, Paul D., Schmidt, Marjanka K., Garcia-Closas, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070183/
https://www.ncbi.nlm.nih.gov/pubmed/27756439
http://dx.doi.org/10.1186/s13058-016-0765-6