Less is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells

BACKGROUND: Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a multifunctional protease implicated in metastatic progression ostensibly due to its ability to degrade extracellular matrix (ECM) components and allow migration of cells through the basement membrane. Despite in vitro studies demons...

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Detalles Bibliográficos
Autores principales: Cepeda, Mario A., Pelling, Jacob J. H., Evered, Caitlin L., Williams, Karla C., Freedman, Zoey, Stan, Ioana, Willson, Jessica A., Leong, Hon S., Damjanovski, Sashko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070195/
https://www.ncbi.nlm.nih.gov/pubmed/27756325
http://dx.doi.org/10.1186/s12943-016-0547-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070195/
https://www.ncbi.nlm.nih.gov/pubmed/27756325
http://dx.doi.org/10.1186/s12943-016-0547-x

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