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Tumour and cellular distribution of activated forms of PR in breast cancers: a novel immunohistochemical analysis of a large clinical cohort

BACKGROUND: The progesterone receptor (PR) is expressed by ∼70% of early breast tumours and is implicated in the progression of breast cancer. In cancerous tissues PR may be activated in the absence of a ligand, or when ligand concentrations are very low, resulting in aberrantly activated PR (APR)....

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Detalles Bibliográficos
Autores principales: Bonneterre, Jacques, Bosq, Jacques, Jamme, Philippe, Valent, Alexander, Gilles, Erard M, Zukiwski, Alexander A, Fuqua, Suzanne A W, Lange, Carol A, O'Shaughnessy, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070234/
https://www.ncbi.nlm.nih.gov/pubmed/27843626
http://dx.doi.org/10.1136/esmoopen-2016-000072