KRAS-driven lung adenocarcinoma: combined DDR1/Notch inhibition as an effective therapy

Understanding the early evolution of cancer heterogeneity during the initial steps of tumorigenesis can uncover vulnerabilities of cancer cells that may be masked at later stages. We describe a comprehensive approach employing gene expression analysis in early lesions to identify novel therapeutic t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ambrogio, Chiara, Nadal, Ernest, Villanueva, Alberto, Gómez-López, Gonzalo, Cash, Timothy P, Barbacid, Mariano, Santamaría, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070278/
https://www.ncbi.nlm.nih.gov/pubmed/27843638
http://dx.doi.org/10.1136/esmoopen-2016-000076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070278/
https://www.ncbi.nlm.nih.gov/pubmed/27843638
http://dx.doi.org/10.1136/esmoopen-2016-000076

Ejemplares similares