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Neuroprotective effects of HTR1A antagonist WAY-100635 on scopolamine-induced delirium in rats and underlying molecular mechanisms

BACKGROUND: Limited surveys have assessed the performance of 5-hydroxytreptamine receptor 1A and its antagonist WAY-100635 in pharmacological manipulations targeting delirium therapies. The purpose of this paper was to assess the central pharmacological activity of WAY-100635 in a rat model of scopo...

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Detalles Bibliográficos
Autores principales: Qiu, Yimin, Chen, Dongmei, Huang, Xiaojing, Huang, Lina, Tang, Liang, Jiang, Jihong, Chen, Lianhua, Li, Shitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070354/
https://www.ncbi.nlm.nih.gov/pubmed/27760517
http://dx.doi.org/10.1186/s12868-016-0300-9