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Clinicopathological features and BRAF(V600E) mutations in patients with isolated hypothalamic-pituitary Langerhans cell histiocytosis

BACKGROUND: Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAF(V600E) mutations and treatments of isolated HPLCH. METHODS: We identified seven patients with isolated HPLCH by re...

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Detalles Bibliográficos
Autores principales: Huo, Zhen, Lu, Tao, Liang, Zhiyong, Ping, Fan, Shen, Jie, Lu, Jingjing, Ma, Wenbing, Zhao, Dachun, Zhong, Dingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070363/
https://www.ncbi.nlm.nih.gov/pubmed/27760550
http://dx.doi.org/10.1186/s13000-016-0548-5