Cargando…

Rigor of cell fate decision by variable p53 pulses and roles of cooperative gene expression by p53

Upon DNA damage, the cell fate decision between survival and apoptosis is largely regulated by p53-related networks. Recent experiments found a series of discrete p53 pulses in individual cells, which led to the hypothesis that the cell fate decision upon DNA damage is controlled by counting the num...

Descripción completa

Detalles Bibliográficos
Autores principales: Murakami, Yohei, Takada, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070454/
https://www.ncbi.nlm.nih.gov/pubmed/27857606
http://dx.doi.org/10.2142/biophysics.8.41