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Proteasome inhibitors attenuated cholesterol-induced cardiac hypertrophy in H9c2 cells

The Ubiquitin proteasome system (UPS) plays roles in protein degradation, cell cycle control, and growth and inflammatory cell signaling. Dysfunction of UPS in cardiac diseases has been seen in many studies. Cholesterol acts as an inducer of cardiac hypertrophy. In this study, the effect of proteaso...

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Detalles Bibliográficos
Autores principales: Lee, Hyunjung, Park, Jinyoung, Kim, Eunice EunKyeong, Yoo, Young Sook, Song, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070706/
https://www.ncbi.nlm.nih.gov/pubmed/26592933
http://dx.doi.org/10.5483/BMBRep.2016.49.5.187