Potentiation of TRAIL killing activity by multimerization through isoleucine zipper hexamerization motif

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a homo-trimeric cytotoxic ligand. Several studies have demonstrated that incorporation of artificial trimerization motifs into the TRAIL protein leads to the enhancement of biological activity. Here, we show that linkage of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Ji Hye, Moon, Ae Ran, Chang, Jeong Hwan, Bae, Jeehyeon, Choi, Jin Myung, Lee, Sung Haeng, Kim, Tae-Hyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070708/
https://www.ncbi.nlm.nih.gov/pubmed/26674343
http://dx.doi.org/10.5483/BMBRep.2016.49.5.245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070708/
https://www.ncbi.nlm.nih.gov/pubmed/26674343
http://dx.doi.org/10.5483/BMBRep.2016.49.5.245

Ejemplares similares