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Neuropeptide Y protects kidney against cisplatin-induced nephrotoxicity by regulating p53-dependent apoptosis pathway

Cisplatin is a platinum-based chemotherapeutic drug for treating various types of cancers. However, the use of cisplatin is limited by its negative effect on normal tissues, particularly nephrotoxicity. Various mechanisms such as DNA adduct formation, mitochondrial dysfunction, oxidative stress, and...

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Detalles Bibliográficos
Autores principales: Kim, Namoh, Min, Woo-Kie, Park, Min Hee, Lee, Jong Kil, Jin, Hee Kyung, Bae, Jae-sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070709/
https://www.ncbi.nlm.nih.gov/pubmed/26728272
http://dx.doi.org/10.5483/BMBRep.2016.49.5.231