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GATA4 negatively regulates bone sialoprotein expression in osteoblasts

GATA4 has been reported to act as a negative regulator in osteoblast differentiation by inhibiting the Dlx5 transactivation of Runx2 via the attenuation of the binding ability of Dlx5 to the Runx2 promoter region. Here, we determine the role of GATA4 in the regulation of bone sialoprotein (Bsp) in o...

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Detalles Bibliográficos
Autores principales: Song, Insun, Jeong, Byung-chul, Choi, Yong Jun, Chung, Yoon-Sok, Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070723/
https://www.ncbi.nlm.nih.gov/pubmed/26973342
http://dx.doi.org/10.5483/BMBRep.2016.49.6.032