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Ablation of Arg-tRNA-protein transferases results in defective neural tube development

The arginylation branch of the N-end rule pathway is a ubiquitin-mediated proteolytic system in which post-translational conjugation of Arg by ATE1-encoded Arg-tRNA-protein transferase to N-terminal Asp, Glu, or oxidized Cys residues generates essential degradation signals. Here, we characterized th...

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Detalles Bibliográficos
Autores principales: Kim, Eunkyoung, Kim, Seonmu, Lee, Jung Hoon, Kwon, Yong Tae, Lee, Min Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070732/
https://www.ncbi.nlm.nih.gov/pubmed/27345715
http://dx.doi.org/10.5483/BMBRep.2016.49.8.087