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Reversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus
Synapse degeneration occurs early in neurodegenerative diseases and correlates strongly with cognitive decline in Alzheimer’s disease (AD). The molecular mechanisms that trigger synapse vulnerability and those that promote synapse regeneration after substantial synaptic failure remain poorly underst...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070786/ https://www.ncbi.nlm.nih.gov/pubmed/27593374 http://dx.doi.org/10.1016/j.cub.2016.07.024 |