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Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial

BACKGROUND: Immunizing human volunteers by mosquito bite with radiation-attenuated Plasmodium falciparum sporozoites (RAS) results in high-level protection against infection. Only two volunteers have been similarly immunized with P. vivax (Pv) RAS, and both were protected. A phase 2 controlled clini...

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Detalles Bibliográficos
Autores principales: Arévalo-Herrera, Myriam, Vásquez-Jiménez, Juan M., Lopez-Perez, Mary, Vallejo, Andrés F., Amado-Garavito, Andrés B., Céspedes, Nora, Castellanos, Angélica, Molina, Karen, Trejos, Johanna, Oñate, José, Epstein, Judith E., Richie, Thomas L., Herrera, Sócrates
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070852/
https://www.ncbi.nlm.nih.gov/pubmed/27760143
http://dx.doi.org/10.1371/journal.pntd.0005070