Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs

The methylfolate trap, a metabolic blockage associated with anemia, neural tube defects, Alzheimer’s dementia, cardiovascular diseases, and cancer, was discovered in the 1960s, linking the metabolism of folate, vitamin B(12), methionine and homocysteine. However, the existence or physiological signi...

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Detalles Bibliográficos
Autores principales: Guzzo, Marissa B., Nguyen, Hoa T., Pham, Thanh H., Wyszczelska-Rokiel, Monika, Jakubowski, Hieronim, Wolff, Kerstin A., Ogwang, Sam, Timpona, Joseph L., Gogula, Soumya, Jacobs, Michael R., Ruetz, Markus, Kräutler, Bernhard, Jacobsen, Donald W., Zhang, Guo-Fang, Nguyen, Liem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070874/
https://www.ncbi.nlm.nih.gov/pubmed/27760199
http://dx.doi.org/10.1371/journal.ppat.1005949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070874/
https://www.ncbi.nlm.nih.gov/pubmed/27760199
http://dx.doi.org/10.1371/journal.ppat.1005949

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