Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

Obesity-related insulin resistance is associated with fatty liver, dyslipidemia, and low plasma adiponectin. Insulin resistance due to insulin receptor (INSR) dysfunction is associated with none of these, but when due to dysfunction of the downstream kinase AKT2 phenocopies obesity-related insulin r...

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Detalles Bibliográficos
Autores principales: Huang-Doran, Isabel, Tomlinson, Patsy, Payne, Felicity, Gast, Alexandra, Sleigh, Alison, Bottomley, William, Harris, Julie, Daly, Allan, Rocha, Nuno, Rudge, Simon, Clark, Jonathan, Kwok, Albert, Romeo, Stefano, McCann, Emma, Müksch, Barbara, Dattani, Mehul, Zucchini, Stefano, Wakelam, Michael, Foukas, Lazaros C., Savage, David B., Murphy, Rinki, O’Rahilly, Stephen, Barroso, Inês, Semple, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070960/
https://www.ncbi.nlm.nih.gov/pubmed/27766312
http://dx.doi.org/10.1172/jci.insight.88766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070960/
https://www.ncbi.nlm.nih.gov/pubmed/27766312
http://dx.doi.org/10.1172/jci.insight.88766

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